Sodium dodecyl sulfate sds, also known as lauryl sulfate, is an ionic detergent that is useful for the rapid disruption of biological membranes. Sodium dodecyl sulfate, synonymously sodium lauryl sulfate or laurilsulfate. Sigmaaldrich offers a number of sodium dodecyl sulfate products. Sodium lauryl sulfate dodecyl sodium sulfate dodecyl sulfate sodium salt sds formula. Sodium lauryl sulfate cas no 1512 einecs ec no 2057881 molecular formula. Sodium dodecyl sulfate sds, 10% solution wash out mouth with water. Sodium dodecyl sulfate sds, white powder, electrophoresis. Oil droplets formed in oilinwater emulsion using sodium dodecyl sulfate sds as emulsifier was stabilized by chi, and microcapsules with multilayers were formed by alternate additions of sds and chi solutions in an emulsion through electrostatic interaction. First aid measures general advice consult a physician. Safety data sheet ghs product identifier other means of identification section 1.
Hazards identification classification of the substance or mixture ghs classification. A chemical safety assessmentreport csacsr has not been. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. Sigmaaldrich offers a number of sodium dodecyl sulfate solution products. Specifications of sodium dodecyl sulfate, synonymously sodium lauryl sulfate appearance. Sodium dodecyl sulfate sds, 10% solution not available. Borate buffer concentrate, to provide a running buffer for the gel. Sigmaaldrich material safety data sheet date printed. Collect contaminated soil for characterization per section. Product name and description sodium dodecyl sulphatesulfate solution 10% trade namebrand not applicable synonyms sds solution. Sds or sls, respectively, is a synthetic organic compound with the formula ch3ch211so4na. Learn more about this chemical, such as how it works and whether its safe. It is a component of many cell lysis buffer formulations, including ripa buffer. Sodium lauryl sulfate 1512 85 sodium sulfate 7757826 6.
Skin contact wash off immediately with soap and plenty of water removing all contaminated clothes and. Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust. Department of biochemistry, kebbi state university of science and technology, pmb 1144, aliero, nigeria. Manual of recommended practices, most recent edition, for details. See section 8 of the msds for personal protective equipment. Safety data sheet aluminium paste with ethyl toyal europe.
Sodium lauryl sulfate sls is found in shampoos, soaps, various beauty and cleaning products, and even some foods. See actual entry in rtecs for complete information. I will be happy to assist you with this question further, before you rate my answer. Fine dust dispersed in air in sufficient concentrations, and. Typical sds or lauryl sulfate preparations are mixtures of several different chain lengths c10 to c18. Use 10% sds sodium dodecyl sulfate solution for any applications requiring sds such as page, nucleic acid hybridization, and cell disruption. Our msds database is an easy to use, do it yourself tool, and best of all. Controlled products regulations and the msds contains all of the. Identification sodium dodecyl sulfate sds, 10% solution sodium dodecyl sulfate sds, 10% solution 3420 central expressway, santa clara ca 95051 3420 central expressway, santa clara ca 95051 trade name. Wear appropriate protective eyeglasses or chemical safety goggles as described by oshas eye and face protection regulations in 29 cfr 1910.
Even though sodium dodecyl sulphate sds is the most frequently studied surfactant, its properties at liquid interfaces are not easily accessible. Sodium dodecyl sulfate other means of identification product no 1894, 4095, l050. Thermo scientific sodium dodecyl sulfate lauryl is standardgrade sds detergent for use in protein polyacrylamide gel electrophoresis page. It is a key component of many reagents used to purify nucleic acids because of its abilities to quickly disrupt the tissue architecture and to inhibit both rnase and.
Effects of dodecanol on the adsorption kinetics of sds at. Details of the supplier of the safety data sheet 2. Dodecyl sodium sulfate recommended use laboratory chemicals. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.
Sodium lauryl sulphate material safety data sheet cas no. It uses sodium dodecyl sulfate sds molecules to help identify and isolate protein molecules. Sodium dodecyl benzene sulphonate sdbs, las can be used as good degreasant for quality leathers. Sodium dodecyl sulphate is catagorised as wgk 2 under the german water classification regulations vwvws. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Flammable in the presence of a source of ignition, through friction or.
Effect of light on selfassembly of aqueous mixtures of. This is mainly caused by the fact that in aqueous solution sds is subject to hydrolysis, by which the homologous dodecanol c12oh is formed. Sodium lauryl sulfate can produce allergic sensitivity reactions. Show this safety data sheet to the doctor in attendance. Dodecyl sodium sulfate dodecyl sulfatesodium salt sds formula. Water spray, dry chemical, alcohol foam, or carbon dioxide. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Provide general or local exhaust ventilation systems to maintain airborne.
In one article, i found that they used pbs4% formol for fixation step instead of trichloroacetic acidtca, and sodium dodecyl sulfate sds. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Material safety data sheet northwest missouri state. Skin contact wash off immediately with soap and plenty of water removing all contaminated clothes and shoes. Apr 06, 2006 i will be happy to assist you with this question further, before you rate my answer. Product and company identification product name dodecyl sulfate sodium salt cat no. Toxicity of sodium dodecyl sulfate to federally threatened and petitioned freshwater mollusk species article pdf available may 2016 with 388 reads how we measure reads. Sodium dodecyl sulfate polyacrylamide gel electrophoresis sdspage of the enzyme complex shows that it comprises an e1. P501 dispose of contentscontainer to hazardous or special waste. Sodium lauryl sulfate increases the per meability of the skin. Physical and chemical properties molecular formula nac12h25oso3. Dodecyl sodium sulfate, dodecyl sulfate sodium salt, lauryl sulfate sodium salt, sds, sodium lauryl sulfate cas number 1512. The user should consider the health hazards and safety information.
Sodium dodecyl benzene sulphonate sdbs, las is a kind of efficient additive which can improve the quality of organic and inorganic chemical products that are easy to absorb moisture and agglomerate. In absorption, metabolism and excretion studies sodium lauryl sulfate had a degenerative effect on the cell membranes because of its protein denaturing properties. Sodium dodecyl sulfate sds is an alkyl sulfate, anionic detergent used frequently in protein electrophoresis and protein solubilization methods. Sodium dodecyl sulfate definition of sodium dodecyl sulfate. Dodecyl sulfate, sodium salt sds, is a are potent protein denaturant and solubilizing agent which bind to proteins cancelling differences in intrinsic charge and converting their shape to rodlike particles whose lengths vary uniquely with molecular weights. Sodium lauryl sulfate dodecyl sodium sulfate dodecyl sulfatesodium salt sds formula. It is an anionic surfactant used in many cleaning and hygiene products. Popular anionic detergent for a variety of protein methods especially useful for denaturing polyacrylamide gel e. Safety data sheet according to 29cfr19101200 and ghs rev. Remove victim to fresh air and keep at rest in a position comfortable for breathing. Jun 30, 2017 material safety data sheet eam worldwide may 31, 2002. Classified as a flammable solid according to dot test methods.
Current trends and future application of sodium dodecyl. This product has been classified in accordance with the hazard criteria of the controlled products regulations and the msds. Sodium dodecyl sulfate sds or sodium lauryl sulfate sls, sometimes written sodium laurilsulfate, is a synthetic organic compound with the formula c h 3 ch 2 11 so 4 na. Thus, the constitutent polypeptides are similar in size to the equivalent components in other eukaryotic branchedchain. Sodium dodecyl sulfate sds is an anionic detergent used to solubilize and denature proteins in protein extraction and sdspage gel electrophoresis. Concentration sodium dodecyl sulphate 1512 2057881 4. Current trends and future application of sodium dodecyl sulphate in biotechnology and surfactant chemistry warra aa. Sodium dodecyl sulfate classified as a flammable solid according to dot test methods. Stop if the exposed person feels sick as vomiting may be dangerous. High levels of skin penetration may occur at even low use concentration.
Continue flushing with plenty of water for at least 15 minutes. Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard. Uses advised against not for food, drug, pesticide or biocidal product use details of the supplier of the safety data sheet emergency telephone number. Sodium dodecyl sulfate an overview sciencedirect topics. Sodium sulfite 007757837 sodium sulfate 007757826 none established. Sds 20% solution is effective in both ionic and anionic conditions. Sodium dodecyl sulfate sds also known as sodium lauryl sulfate is an anionic surfactant solution used as an adjuvant in lysing cells during dna extraction e. Sodium lauryl sulfate is an anionic surfactant used in cosmetics and industrial chemicals as a cleansing agent. Effect of light on selfassembly of aqueous mixtures of sodium dodecyl sulfate and a cationic, bolaform surfactant containing azobenzene f.
Sodium dodecyl sulfate sds, white powder, electrophoresis, fisher bioreagents poly pail. In one article, i found that they used pbs4% formol for fixation step instead of trichloroacetic acidtca, and sodium dodecyl sulfate sds instead of tris base to solubilize protein bound. Sds solution 10% safety data sheet the ncbe university of. In the first step, more than 90% of free ds precipitates out from protein solution, the method being poorly sensitive to dodecyl sulfate kcl ratio from almost no sds to 10%. Pdf toxicity of sodium dodecyl sulfate to federally. A new twostep precipitation method removes freesds and. Technical data sheet 299 sodium dodecyl sulfate sds. First aid measures eye contact rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Sodium dodecyl sulfate other means of identification product no 1894, 4095, l050 recommended use and restriction on use recommended use. Sdspage sodium dodecyl sulfate polyacrylamide gel electrophoresis, the use of sodium dodecyl sulfate sds, also known as sodium lauryl sulfate and polyacrylamide gel largely eliminates the influence of the structure and charge, and proteins are separated solely based on polypeptide chain length.
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